Journal of Hematology

Farhad Ravandi, MD, Professor
Janiece and Stephen A. Lasher Professor of Medicine
Chief, Section of Acute Myeloid Leukemia
Department of Leukemia
The University of Texas MD Anderson Cancer Center, Texas, USA  Read more...

ISSN 1927-1212 print | ISSN 1927-1220 online | Bimonthly | Open Access | Aims and Scope

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  • Incidence and Risk of Hematological Adverse Events Associated With Immune Checkpoint Inhibitors: A Systematic Literature Review and Meta-Analysis

    Immune checkpoint inhibitors (ICIs) have been a breakthrough in cancer therapy. ICI therapy is generally better tolerated than cytotoxic chemotherapy; however, hematological adverse events (AEs) have not been fully analyzed.

  • Mature Type T-Lymphoblastic Leukemia/Lymphoma Presenting With Isolated Central Nervous System Symptomatology in a Patient With Giant Cell Arteritis on Long-Term Steroid Treatment

    T-lymphoblastic leukemia/lymphoma (T-ALL/T-LBL) is a malignancy comprised of T-lymphoblasts that can present as one of four clinical subtypes (pro-T, pre-T, cortical T, and mature T).

  • Acute Myeloid Leukemia Following Myeloproliferative Neoplasms: A Review of What We Know, What We Do Not Know, and Emerging Treatment Strategies

    Acute myeloid leukemia (AML) arising from myeloproliferative neoplasms (MPNs) represents a small subtype of secondary AML (sAML). This entity is well known to be associated with poor responses to available treatment options and dismal outcomes.

  • Treatment of Light Chain Deposition Disease: A Systematic Review

    Light chain deposition disease (LCDD) is a rare hematologic disorder that can affect any organ but predominantly involves the kidneys. Existing literature is limited to case reports and small single-center retrospective series, explaining the lack of any treatment algorithms and management guidelines for patients with this disorder.

  • Hematological, Biochemical Properties, and Clinical Correlates of Hemoglobin S Variant Disorder: A New Insight Into Sickle Cell Trait

    The sickle cell trait (SCT) disorder possesses a clinical heterogeneity ranging from a symptomless condition to sudden death. This study aimed to develop a diagnostic approach that helps the characterization and identification of SCT from normal subjects and sickle cell disease (SCD) patients, and to assess its severity.







Neutropenic Enterocolitis: An Uncommon, but Fearsome Complication of Leukemia
Neutropenic enterocolitis (NEC) is a life-threatening condition occurring in severely neutropenic patients, following intensive chemotherapy for leukemia. Its pathogenesis is not entirely understood and believed to be multifactorial, including mucosal injury as a result of cytotoxic drugs, profound neutropenia, impaired host defense and possibly microbiota changes. Full Text

Survival in Elderly Patients Diagnosed With Acute Myeloid Leukemia: A Hospital-Based Study
Acute myeloid leukemia (AML) is a hematological neoplasm that is more frequent in elderly patients. The objective of this study was to evaluate elderly patients’ survival with de novo AML and acute myeloid leukemia myelodysplasia-related (AML-MR), treated with intensive and less-intensive chemotherapy and supportive care. Full Text

Key Clinical Image

De-Novo B-Cell Prolymphocytic Leukemia
B-cell prolymphocytic leukemia (B-PLL) is a rare B-cell neoplasm that typically presents with splenomegaly, a rising white blood cell count, and may or may not have B symptoms. The diagnosis usually requires a bone marrow biopsy and aspirate with flow cytometry and cytogenetic studies. At least 55% of the lymphocytes in the peripheral blood must be prolymphocytes to be defined as B-PLL. Full Text

Current Issue


Vol. 12, No. 2, Apr 2023

Table of Contents


Neutropenic Enterocolitis: An Uncommon, but Fearsome Complication of Leukemia Abstract HTML PDF
Rodrick Babakhanlou, Farhad Ravandi-Kashani, Dimitrios P. Kontoyiannis 59-65

Original Article

Incidence and Risk of Hematological Adverse Events Associated With Immune Checkpoint Inhibitors: A Systematic Literature Review and Meta-Analysis Abstract HTML PDF Suppl1 Suppl2 Suppl3 Suppl4 Suppl5 Suppl6 Suppl7 Suppl8
Takuma Ohashi, Kaoru Takase-Minegishi, Ayaka Maeda, Naoki Hamada, Ryusuke Yoshimi, Yohei Kirino, Hiroshi Teranaka, Hiroyoshi Kunimoto, Maki Hagihara, Kenji Matsumoto, Ho Namkoong, Nobuyuki Horita, Hideaki Nakajima 66-74

Case Report

Primary Diffuse Large B-Cell Lymphoma of the Bone Abstract HTML PDF
Binoy Yohannan, Adan Rios 75-81
De-Novo B-Cell Prolymphocytic Leukemia Abstract HTML PDF
Sasmith R. Menakuru, Janet Roepke, Salahuddin Siddiqui 82-86
A Meningioma Mimic and Distinct Subtype of Primary Central Nervous System Lymphoma: Primary Dural Lymphoma Abstract HTML PDF
Sushanth Sreenivasan, Risha Solanki, Pragnan Kancharla, Cyrus Khan, Yazan Samhouri 87-91
Treatment and Response Evaluation Challenges in a Pregnant Woman With B-Cell Lymphoblastic Leukemia and Li-Fraumeni Syndrome Abstract HTML PDF
Bjarte Skoe Erikstein, Aymen Bushra Ahmed, Rakel Brendsdal Forthun, Friedemann Leh, Bjørn Tore Gjertsen, Håkon Reikvam 92-99
Acute Promyelocytic Leukemia Treatment Masking Hepatic Tuberculosis: A Management Dilemma Abstract HTML PDF
Kimberly Boldig, Amy Kiamos, Trevanne Matthews-Hew, Reeba Omman, Walter Quan 100-104

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Journal of Hematology, bimonthly, ISSN 1927-1212 (print), 1927-1220 (online), published by Elmer Press Inc.                            
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