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Highlights |
- Harnessing the Immune System: An Effective Way to Manage Diffuse Large B-Cell Lymphoma
Diffuse large B-cell lymphoma (DLBCL) is a heterogenous hematological disorder with malignant potential controlled by immunological characteristics of the tumor microenvironment. Rapid breakthrough in the molecular pathways has made immunological approaches the main anchor in the management of DLBCL, with or without chemotherapeutic agents.
Read More >> - Incidence and Risk of Hematological Adverse Events Associated With Immune Checkpoint Inhibitors: A Systematic Literature Review and Meta-Analysis
Immune checkpoint inhibitors (ICIs) have been a breakthrough in cancer therapy. ICI therapy is generally better tolerated than cytotoxic chemotherapy; however, hematological adverse events (AEs) have not been fully analyzed.
Read More >> - Mature Type T-Lymphoblastic Leukemia/Lymphoma Presenting With Isolated Central Nervous System Symptomatology in a Patient With Giant Cell Arteritis on Long-Term Steroid Treatment
T-lymphoblastic leukemia/lymphoma (T-ALL/T-LBL) is a malignancy comprised of T-lymphoblasts that can present as one of four clinical subtypes (pro-T, pre-T, cortical T, and mature T).
Read More >> - Acute Myeloid Leukemia Following Myeloproliferative Neoplasms: A Review of What We Know, What We Do Not Know, and Emerging Treatment Strategies
Acute myeloid leukemia (AML) arising from myeloproliferative neoplasms (MPNs) represents a small subtype of secondary AML (sAML). This entity is well known to be associated with poor responses to available treatment options and dismal outcomes.
Read More >> - Treatment of Light Chain Deposition Disease: A Systematic Review
Light chain deposition disease (LCDD) is a rare hematologic disorder that can affect any organ but predominantly involves the kidneys. Existing literature is limited to case reports and small single-center retrospective series, explaining the lack of any treatment algorithms and management guidelines for patients with this disorder.
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| Local and Systemic Immunity During Five Vaccinations Against SARS-CoV-2 in Zanubrutinib-Treated Patients With Chronic Lymphocytic Leukemia |
Key Clinical Image |
![]() Sickle Cell Trait: Is It Always Benign? |
Current Issue |
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Vol. 12, No. 4, Aug 2023
Table of Contents
Review
Harnessing the Immune System: An Effective Way to Manage Diffuse Large B-Cell Lymphoma | Abstract HTML PDF |
Nathan Visweshwar, Juan Felipe Rico, Robert Killeen, Arumugam Manoharan | 145-160 |
doi: https://doi.org/10.14740/jh1112 |
Original Article
Could the Crosstalk Between Myeloid-Derived-Suppressor Cells and Regulatory T Cells Have a Role in Beta-Thalassemia? | Abstract HTML PDF |
Asmaa M. Zahran, Omnia El-Badawy, Eman R. Badawy, Khalid I. Elsayh, Eman F. Gad, Khaled Saad![]() |
161-169 |
doi: https://doi.org/10.14740/jh1149 |
Short Communication
Local and Systemic Immunity During Five Vaccinations Against SARS-CoV-2 in Zanubrutinib-Treated Patients With Chronic Lymphocytic Leukemia | Abstract HTML PDF Suppl1 |
Maria Andersson, Jinghua Wu, David Wullimann, Yu Gao, Mikael Aberg, Sandra Muschiol, Katie Healy, Sabrina Naud, Gordana Bogdanovic, Marzia Palma, Hakan Mellstedt, Puran Chen, Hans-Gustaf Ljunggren, Lotta Hansson, Margaret Sallberg Chen, Marcus Buggert, Hanna M. Ingelman-Sundberg, Anders Osterborg | 170-175 |
doi: https://doi.org/10.14740/jh1140 |
Case Report
Reduced-Intensity Anthracycline-Free Chemoimmunotherapy in Elderly Patients With Newly Diagnosed or Relapsed Diffuse Large B-Cell Lymphoma | Abstract HTML PDF |
Binoy Yohannan, Adan Rios | 176-186 |
doi: https://doi.org/10.14740/jh1144 |
Leukostasis With Isolated Central Nervous System Involvement in Chronic Phase of Chronic Myelogenous Leukemia | Abstract HTML PDF |
Won Jin Jeon![]() |
187-196 |
doi: https://doi.org/10.14740/jh1150 |
Letter to the Editor
Hemolytic Anemia Requiring Splenectomy in Leigh-Like Syndrome due to the Variant m.10191T>C in MT-ND3 | Abstract HTML PDF |
Shaundra M. Newstead![]() ![]() |
197-200 |
doi: https://doi.org/10.14740/jh1122 |