Acute Cutaneous Flare and Hemophagocytosis: An Unusual Presentation of Adult Anaplastic Large Cell Lymphoma

Ralph Yachoui, Patrick M Cronin

Abstract


    Hemophagocytic lymphohistiocytosis (HLH), also known as hemophagocytic syndrome, is a disorder characterized by the pathologic activation and proliferation of histiocytes, mainly in the bone marrow, liver, spleen and lymph nodes. Although HLH is frequently associated with lymphomas, it is a rare presentation of anaplastic large cell lymphoma (ALCL). We report a case of anaplastic large cell lymphoma (ALCL) in an adult manifested as generalized cutaneous nodules and fulminant hemophagocytosis.




doi: http://dx.doi.org/10.4021/jh35e

Keywords


Hemophagocytic lymphohistiocytosis; Anaplastic large cell lymphoma

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Journal of Hematology, quarterly, ISSN 1927-1212 (print), 1927-1220 (online), published by Elmer Press Inc.            
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