Journal of Hematology, ISSN 1927-1212 print, 1927-1220 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Hematol and Elmer Press Inc
Journal website https://www.thejh.org

Case Report

Volume 11, Number 2, April 2022, pages 71-76

A Case of Isolated Myeloid Sarcoma Associated With Germline EGFR T790M Variant: The Importance of Recognizing Potential Germline Variants on Somatic Tumor Sequencing Panels

Figures

Figure 1.
Figure 1. Family pedigree of the patient. The patient is indicated as the proband with an arrow. Assigned females at birth are represented as circles; assigned males at birth are represented as squares. Lines through a symbol indicate that the individual is deceased. d: deceased at age.
Figure 2.
Figure 2. (a) CT scan of the chest obtained at diagnosis revealed a right posterior mediastinal mass with scattered right lung nodules. A representative pulmonary nodule is indicated by the red circle. (b) An MRI of the spine was performed to evaluate acute bilateral lower extremity weakness. This revealed a 10-cm posterior mediastinal mass (arrow) extending into the thoracic spinal canal from T2 to T9 resulting in moderate-to-severe spinal stenosis. CT: computed tomography; MRI: magnetic resonance imaging.