Journal of Hematology, ISSN 1927-1212 print, 1927-1220 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Hematol and Elmer Press Inc
Journal website http://www.thejh.org

Original Article

Volume 2, Number 1, June 2013, pages 8-13

Correlation of Bone Marrow Aspirate, Biopsies and Touch Imprint Findings in Pancytopenia

Figures

Figure 1.
Figure 1. BMA showing Megaloblastic and normoblastic maturation, (Leishmann stain 100 ×).
Figure 2.
Figure 2. BMB showing a hypocellular marrow, (Hematoxylin and eosin stain 10 ×).
Figure 3.
Figure 3. BMA showing neoplastic plasma cells, (Leishmann stain 40 ×).
Figure 4.
Figure 4. BMB showing metastatic adenocarcinoma, (Hematoxylin and eosin stain 40 ×)

Tables

Table 1. Clinical Features of Patients Presenting With Pancytopenia
 
SymptomsNo. of casesPercentage
Fever3866%
Generalized Weakness2950%
Pallor2746%
Easy Fatigability2340%
Splenomegaly1424%
Lymphadenopathy59%
Bleeding59%
Hepatomegaly47%
Skin Rashes23%

 

Table 2. Causes of Pancytopenia (n = 58)
 
DiagnosisNo. of casesPercentage
Megaloblastic anemia2339.65%
Nutritional anemia1424.13%
Aplastic anemia712.06%
Acute Lymphoblastic Leukemia46.8%
Multiple Myeloma35.1 %
Hemophagocytic Syndrome11.7%
Acute Myeloid Leukemia11.7%
Malaria11.7%
Waldenstrom’s Macroglobulinemia11.7%
Hairy cell leukaemia11.7%
Hodgkin lymphoma11.7%
Metastasis11.7%
Total58100%

 

Table 3. Bone Marrow Cellularity
 
CellularityNo. of casesPercentage
Hypercellular3051.72%
Normocellular2136.02%
Hypocellular712.06%
Total58100%

 

Table 4. Positive Correlation Between Bone Marrow Aspiration and Bone Marrow Biopsy
 
DiagnosisNo. of casesPercentage
Megaloblastic anemia2350%
Nutritional anemia1123.9%
Aplastic anemia613.04%
Malaria12.17%
AML12.17%
MM36.5 %
Waldenstrom’s Macroglobulinemia12.17%
Total44100%