Journal of Hematology, ISSN 1927-1212 print, 1927-1220 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Hematol and Elmer Press Inc
Journal website http://www.thejh.org

Review

Volume 3, Number 4, December 2014, pages 95-106


Anemia in the Elderly Population

Tables

Table 1. Types of Anemia in the Elderly in Patients 65 Years and Older
 
StudySubjectsIDA %B12/folate deficiency %ACD %UA %Renal insufficiency %
IDA: iron deficiency anemia; ACD: anemia of chronic disease.
Bach et al, 2014 [16]4,177AID: 14.4; FID: 28.2B12: 2.0; B6: 6.762.111.3
Guralnik, 2004 [17]2,09616.6B12: 5.9; B6: 6.419.733.68.2
Shavelle, 2012 [18]7,171263911
Tettamanti, 2010 [19]8,7741610.117.426.415
Price, 2011 [20]190126354
Artz, 2011 [21]17425.34.69.843.73.4
Ferrucci, 2010 [22]58217.410.524.437.210.5
den Elzen, 2013 [23]49011.45.320.225.47

 

Table 2. Distribution of Types of Anemia in Persons Age 65 and Older in US
 
AnemiaNumber in the USAll anemia %
ACI: anemia of chronic inflammation. Reproduced with permission from Guralnick et al [17].
With nutrient deficiency
  Iron only466,71516.6
  Folate only181,4716.4
  B12 only165,7015.9
  Folate and B1256,4362.0
  Iron with folate or B12 or both95,22195.221
  Total965,54434.3
Without nutrient deficiency
  Renal insufficiency only229,6868.2
  ACI, no renal insufficiency554,28119.7
  Renal insufficiency and ACI120,1694.3
  UA945,19533.6
  Total1,849,33165.7

 

Table 3. Potential Mechanism of UA in the Elderly.
 
Sarcopenia
Oxidative stress
Quantitative/qualitative alterations in stem cell physiology
Decrease in sex steroids
Polypharmacy
Blunting of hypoxia/erythropoietin sensing mechanism