Journal of Hematology, ISSN 1927-1212 print, 1927-1220 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Hematol and Elmer Press Inc
Journal website http://www.thejh.org

Original Article

Volume 5, Number 1, March 2016, pages 17-24

Quantitative Expression of Toll-Like Receptors TLR-7 and TLR-9 on Peripheral Blood Mononuclear Cells in Leukemias

Figures

Figure 1.
Figure 1. Comparison of the expression of TLR-7/GAPDH mRNA in PBMCs between different groups.
Figure 2.
Figure 2. Comparison of the expression of TLR-9/GAPDH mRNA in PBMCs between different groups.
Figure 3.
Figure 3. Relative expression of TLR-7 by RT-PCR data in different studied groups and controls.
Figure 4.
Figure 4. Relative expression of TLR-9 by RT-PCR data in different studied groups and controls.

Tables

Table 1. Comparison Between Peripheral Blood Expression of TLR-7/GAPDH mRNA in PBMCs in Different Studied Groups and Controls
 
Controls (n = 30)Acute myeloid leukemia (n = 15)Acute lymphoblastic leukemia (n = 15)Chronic myeloid leukemia (n = 15)Chronic lymphocytic leukemia (n = 15)
*P < 0.05.
TLR-7, range (mean ± SD)0.929 - 1.341 (1.023 ± 0.061)1.37 - 1.51 (1.44 ± 0.126)1.361 - 1.482 (1.447 ± 0.1611)0.272 - 0.396 (0.341 ± 0.16)1.447 - 1.491 (1.462 ± 0.071)
T2.112.988.012.11
P0.013*0.011*0.001*0.016*

 

Table 2. Comparison Between Peripheral Blood Expression of TLR-9/GAPDH mRNA in PBMCs in Different Studied Groups and Controls
 
Controls (n = 30)Acute myeloid leukemia (n = 15)acute lymphoblastic leukemia (n = 15)Chronic myeloid leukemia (n = 15)Chronic lymphocytic leukemia (n = 15)
*P < 0.05.
TLR-9, range (mean ± SD)0.943 - 1.492 (1.245 ± 0.112)0.941 - 1.571 (1.35 ± 0.187)0.9628 - 1.279 (1.162 ± 0.191)0.380 - 0.540 (0.442 ± 0.161)1.36 - 1.51 (1.425 ± 0.11)
T0.981.687.252.85
P0.3650.0710.001*0.031*