Journal of Hematology, ISSN 1927-1212 print, 1927-1220 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Hematol and Elmer Press Inc
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Case Report

Volume 5, Number 1, March 2016, pages 30-33

A Novel Approach for Treatment of Cold Agglutinin Syndrome-Related Severe Hemolysis


Figure 1.
Figure 1. Time trend in haptoglobin and lactate dehydrogenase (LDH) (A) and hemoglobin (B). Day 0 was when the consult was received. Berinert was administered on day 0 to day 8 (except day 6). Rituximab was given on days 4 and 11. The other two doses were given as outpatient. Prednisone 1 mg/kg/day was started on day 0 and was continued till tapered off as outpatient.
Figure 2.
Figure 2. Levels of hemoglobin (A) and haptoglobin (B) before and 2 h after the administration of Berinert showing an immediate improvement in hemolysis.